Manchester United could clinch qualification for the Champions League last 16 when they host Benfica on Tuesday.
Jose Mourinho has no fresh injury concerns and they boast a 100 per cent record in Group A after three matches.
United will qualify from Group A if they win and CSKA Moscow fail to beat Basel, or if United draw and CSKA lose.
Paris Saint-Germain have enjoyed a perfect start to their Champions League campaign currently heading the standings in Group B with a maximum nine points.
They host Anderlecht and if they achieve a better result than Celtic do against Bayern Munich the French side will be guaranteed a place in the knock-out stages with two group matches still to be played.
Group C leaders Chelsea head to the Italian capital for their match against Roma who sit second in the group, two points behind the leaders with the ability to leapfrog them with a victory at home.
When the teams met at Stamford Bridge, Chelsea could only manage a 3-3 draw.
A win for Chelsea would put them five points clear atop the table with just two games left to play.
Sporting CP face Juventus in Lisbon with the Portuguese side sitting third in the Group D standings, three points behind their visitors and six adrift of leaders Barcelona.
Fresh off a 2-1 win over Sporting a little less than a fortnight ago, Juventus know that a win in Lisbon, will secure passage to knockout round for the fourth year in a row.